EVALUASI SIFAT FISIK SEDIAAN FACIAL WASH EKSTRAK ETANOL DAUN SIRIH CINA (Paperomia pellucidaL.)SEDIAAN FACIAL WASH EKSTRAK ETANOL DAUN SIRIH CINA (Paperomia pellucidaL.)
Keywords:
Daun Sirih Cina, facial wash, Propionibacterium acnesAbstract
If dirt on the face is not cleaned over time, it will accumulate into blackheads and pimples. Acne can also occur due to underlying blockage and inflammation, usually caused by the bacteria Propionibacterium acnes. Ethanol extract of Chinese betel leaves contains alkaloids, tannins, lipids and essential oils which have antibacterial properties. The aim of this research is to find out whether the facial wash formulation can meet the requirements for a good physical properties test and to find out whether the Chinese betel leaf extract (Paperomia pellucida L. Kunth) facial wash preparation has inhibitory power against P.acnes. This research is experimental research. Physical property tests carried out include organoleptic, pH, foamability and viscosity tests. Antibacterial activity testing was carried out using the diffusion method. Facial wash preparations from Chinese betel leaf extract (Paperomia pellucida L. Kunth) are made with concentrations of 0% (F0), 10% (F1), 15% (F2), 20% (F3). The results of the antibacterial activity test were tested using one way anova statistics. The research results showed that the facial wash preparation met the requirements for a good physical properties test and there was no significant difference between the formulas. The average results of the positive control antibacterial activity test for clindamycin had an inhibitory power of 19.53 ± 0.38 mm (strong), the facial wash preparation of Chinese betel leaf ethanol extract with a concentration of 10% was 8.90 ± 0.97 mm ( moderate), 15% concentration 12.00 ± 0.24 mm (strong), 20% concentration 13.33 ± 0.38 mm (strong), and negative control 0 ± 0 (not inhibiting. This study can be concluded that facial wash ethanol extract of Chinese betel leaves can inhibit antibacterial activity and the significant value is 0.000 <0.05, which means there is a difference in each concentration with the positive control
References
Aviany, H. B., & Pujiyanto, S, 2020. Analisis Efektivitas Probiotik di Dalam Produk Kecantikan sebagai Antibakteri terhadap Bakteri Staphylococcus epidermidis. Jurnal Berkala Bioteknologi, 3(2), 24–31.
Endriyatno, N. C., & Puspitasari, D. N, 2023. Formulasi Krim Ekstrak Daun Sirih Cina (Peperomia Pellucida L.) Dengan Variasi Konsentrasi Trietanolamin Dan Asam Stearat. Forte Journal, 3(1), 33–42.
Evi Marlina, Naelaz Zukhruf Wakhidatul Kiromah, & Titi Pudji Rahayu, 2022 Formulasi Sediaan Antioksidan Facial Wash Ekstrak Metanol Daun Ganitri (Elaeocarpus Ganitrus Roxb.) Dengan Variasi Sodium Lauril Sulfat Sebagai Surfaktan. Jurnal Ilmiah Manuntung, 8(1), 181–190.
Gunarti, N. S. 2018. Pemanfaatan Ekstrak Daun Jambu Biji (Psidium Guazava) Sebagai Gel Facial Wash Antijerawat. Pharma Xplore : Jurnal Ilmiah Farmasi, 3(2)
Harris, M. V., Darmanto, Y. S., & Riyadi, P. H, 2015, Pengaruh Kolagen Tulang Ikan Air Tawar Yang Berbeda Terhadap Karakteristik Fisik Dan Kimia Sabun Mandi Padat C. 5(1), 2442–4145
Hasanah, N., & Novian, D. R. 2020. Daya Hambat Ekstrak Daun Belimbing Wuluh (Averrhoa bilimbi L) Terhadap Bakteri Penyebab Jerawat (Propionibacterium acnes). Parapemikir : Jurnal Ilmiah Farmasi, 9(1), 46
Imansyah, M. Z., & Hamdayani, S, 2022, Uji Aktivitas Ekstrak Etanol Daun Sirih Cina (Peperomia Pellucida L.) Terhadap Bakteri Propionibacterium Acnes, Jurnal Kesehatan Yamasi Makassar, 6(1), 40–47.
Irsyad, M, 2013, Standardisasi Ekstrak Etanol Tanaman Katumpangan Air ( Peperomia Pellucida L . Kunth ) Standardisasi Ekstrak Etanol Tanaman Katumpangan Air ( Peperomia Pellucida L . Kunth ) (Issue September).
Melian, E, 2018, Formulasi Kaolin Facial Wash Dengan Variasi Konsentrasi Sodium Laurileter Sulfat (Sles) Dan Uji Daya Bersihnya Terhadap Bakteri Penyebab Jerawat (Propionibacterium Acnes), Skripsi
Noor, Siti Umrah, & Nurdyastuti, D, 2008, Lauret 7 Sitrat Sebagai Detergensia Dan Peningkat Busa Pada Sabun Cair Wajah Glysine Soja (Pp. 39–47).
P Putri, Winda Anggia Dwi, 2021, Formulasi Sediaan Facial Wash Ekstrak Etanol Daun Kemangi (Ocimum Basilicum L) (Issue March).
Putu, N., Cahya, P., Putu, N., Dharma, R., & Puspa, K. A. 2023. Uji Aktivitas Antioksidan Gummy Candy Ekstrak Daun Sirih Cina ( Peperomia pellucida L . Kunth ) dengan Metode DPPH. 3(3), 436–446.
Sarosa, A. H., P, H. T., Santoso, B. I., Nurhadianty, V., & Cahyani, C, 2018 Pengaruh Penambahan Minyak Nilam Sebagai Bahan Aditif Pada Sabun Cair Dalam Upaya Meningkatkan Daya Antibakteri Terhadap Staphylococcus aureus. Indonesian Journal Of Essential Oil, 3(1), 1–8
Sudjono, T. A, 2015 Pengaruh Konsentrasi Gelling Agent Carbomer 934 Dan Hpmc Pada Formulasi Gel Lendir Bekicot (Achatina Fulica) Terhadap Kecepatan Penyembuhan Luka Bakar Pada Punggung Kelinci. Pharmacon: Jurnal Farmasi Indonesia, 13(1)
Tambunan, S., & Sulaiman, T. N. S, 2019 Gel Formulation of Lemongrass Essential Oil with HPMC and Carbopol Bases. Majalah Farmaseutik, 14(2), 87Widiawati, D. (2014). PERBEDAAN HASIL PENYEMBUHAN KULIT WAJAH BERJERAWAT ANTARA Masker Lidah Buaya Dengan Masker Non Lidah Buaya. E-Jurnal, 03(01), 217–225.
wirawan et al. (2009). Pengaruh Penggunaan Sodium Lauryl Ether Sulfate Sebagai Deterjen Terhadap Daya Bersih Dan Ketinggian Busa. 07(1).
Yuliani, D., Keumala Dewi, I., & Marhamah, S, 2022, Efektivitas Ekstrak Daun Sirih Cina (Peperomia Pellucida) Terhadap Pertumbuhan Bakteri Propionibacterium Acnes Dan Tinjauannya Menurut Pandangan Islam, Jurnal Sosial Sains, 2(1), 173–181.https://doi.org/10.36418/sosains.v2i1.333
Yuniarsih, N., Akbar, F., & Lenterani, I, 2020, Formulasi Dan Evaluasi Sifat Fisik Facial Wash Gel Ekstrak Kulit Buah Naga Merah ( Hylocereus Polyrhizus ) Dengan Gelling Agent Carbopol, Jurnal Pharma Xplore, 5(2), 57–67
